Autor: |
H C, Meissner, D Y, Leung |
Rok vydání: |
1995 |
Předmět: |
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Zdroj: |
Current Opinion in Rheumatology. 7:455-480 |
ISSN: |
1040-8711 |
DOI: |
10.1097/00002281-199509000-00016 |
Popis: |
Although a general consensus on the etiology of Kawasaki syndrome has not been reached, increasing evidence suggests that this illness represents a response to a superantigen. This conclusion is based on the observations of the immunologic changes that characterize the acute stages of illness as well as on the demonstrated association with toxin-producing bacteria in the pharynx and gastrointestinal tract. Therapy with intravenous gamma globulin and high-dose aspirin remains the standard of care for acute disease. Long-term follow-up of increasing numbers of children has confirmed that few properly treated children are at risk for the development of coronary artery abnormalities due to this illness. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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