| Autor: |
Renée Turzanski Fortner, Kristen D Brantley, Shelley S Tworoger, Rulla M Tamimi, Bernard Rosner, Maryam S Farvid, Michelle D Holmes, Walter C Willett, A Heather Eliassen |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
JNCI Cancer Spectrum. 7 |
| ISSN: |
2515-5091 |
| Popis: |
Background Physical activity is generally associated with better outcomes following diagnosis; however, few studies have evaluated change in pre- to postdiagnosis activity and repeated measures of activity by intensity and type. Methods We evaluated physical activity and survival following a breast cancer diagnosis in the Nurses’ Health Study and Nurses’ Health Study II (n = 9308 women, n = 1973 deaths). Physical activity was evaluated as updated cumulative average of metabolic equivalent of task (MET)-h/wk (assigned per activity based on duration and intensity) and change in pre- to postdiagnosis activity. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results Higher postdiagnosis activity was inversely associated with breast cancer–specific mortality in categories from ≥9 MET-h/wk (vs Conclusions Physical activity was associated with lower risk of death following diagnosis. Increased pre- to postdiagnosis activity corresponding to at least 1-3 h/wk of walking was associated with lower risk of death. These results provide further impetus for women to increase their activity after a breast cancer diagnosis, though reverse causation cannot be fully excluded. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
