Near‐infrared heating of skin to delineate non‐melanoma skin cancer lesions: A pilot study
| Autor: | Kevin Jordan, Corey C. Moore, Kiersten Pianosi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms Erythema Pilot Projects Dermatology 01 natural sciences Heating 010309 optics Lesion 030207 dermatology & venereal diseases 03 medical and health sciences Hyperaemia 0302 clinical medicine 0103 physical sciences Humans Medicine Melanoma integumentary system business.industry Significant difference Margins of Excision medicine.disease Initial lesion Histopathology Radiology medicine.symptom Skin cancer business Non melanoma |
| Zdroj: | Skin Research and Technology. 27:234-240 |
| ISSN: | 1600-0846 0909-752X |
| Popis: | Background Surgical excision is a mainstay of treatment for non-melanoma skin cancer (NMSC); improving margin delineation can reduce the need for further monitoring/treatment. The objective of this pilot study was to determine if near-infrared radiation (NIR) application to skin causes visible changes in normal and NMSC skin, to help delineate margins. Materials/methods Eleven biopsy-proven NMSC lesions were included. The skin was then heated under a 175W NIR heating bulb; margins were traced onto acetate film before and after heating. Lesions were then randomly assigned to excision based on pre- or post-heating margins. Composite images were generated by overlaying the heat and no-heat lesion contours. All specimens were sent for histopathology. Results The range of closest margins in the control group was 2.0-3.0 mm with a median of 2.0 mm; the range in the intervention group was 4.0-9.0 mm with a median of 5.0 mm. Composite images showed larger heat contours when the initial lesion was larger. There was a statistically significant difference between the two groups. Overall, NIR light caused visible hyperaemia to skin, and more intense erythema to malignant skin lesions. Conclusion Near-infrared light may have use in an outpatient setting for skin cancer delineation, possibly reducing the rate of positive margins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|