Congenital Transmission of Trypanosoma cruzi in Non-Endemic Areas: Evaluation of a Screening Program in a Tertiary Care Hospital in Barcelona, Spain
| Autor: | Elena Sulleiro, Susana Otero, Anna Suy, Concepción Figueras, María Espiau, Israel Molina, Andrea Martín-Nalda |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Chagas disease medicine.medical_specialty Trypanosoma cruzi Enzyme-Linked Immunosorbent Assay Tertiary Care Centers Pregnancy Trypanosomiasis Virology Internal medicine parasitic diseases Disease Transmission Infectious medicine Humans Seroprevalence biology Transmission (medicine) business.industry Infant Newborn Articles Tertiary care hospital medicine.disease biology.organism_classification Infectious Diseases Spain Immunology Female Parasitology Congenital transmission business |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 87:832-836 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2012.12-0152 |
| Popis: | The impact of Chagas disease is no longer restricted to endemic areas. The aim of this study is to evaluate a 2-year period of a vertical transmission screening program of Trypanosoma cruzi infection in a tertiary care hospital in Barcelona (Spain). Two enzyme-linked immunosorbent assays (recombinant and crude antigen) were performed in parallel to pregnant women at risk of T. cruzi infection. Discordant results were confirmed by a third diagnostic test. In the case of a positive result, the newborn was tested at birth and after 8 months of life. A total of 1,473 women met the inclusion criteria for the screening program with a resulting seroprevalence for T. cruzi of 3.5% (2.2-5.2% 95% confi- dence interval (95% CI)). One case of congenital infection was identified. Screening programs for vertically transmitted T. cruzi acute infection are beneficial in non-endemic areas for early detection and treatment of acute infection. |
| Databáze: | OpenAIRE |
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