The association of dietary patterns with high-risk human papillomavirus infection and cervical cancer: A cross-sectional study in Italy
| Autor: | Aurora Scalisi, Antonella Agodi, Annalisa Quattrocchi, Martina Barchitta, Andrea Maugeri, O Agrifoglio |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Mediterranean diet score
Mediterranean diet Cross-sectional study Healthy Diet Uterine Cervical Neoplasms Mediterranean Diet Mediterranean Logistic regression Food group Eating 0302 clinical medicine Risk Factors Surveys and Questionnaires Odds Ratio Medicine 030212 general & internal medicine Western diet Cervical cancer Nutrition and Dietetics Middle Aged cervical intraepithelial neoplasia principal component analysis prudent diet nutrition Quartile Italy 030220 oncology & carcinogenesis Female Diet Healthy lcsh:Nutrition. Foods and food supply Adult medicine.medical_specialty Principal component analysis lcsh:TX341-641 Cervical intraepithelial neoplasia Risk Assessment Article Odds 03 medical and health sciences Internal medicine Humans Cervical Intraepithelial Neoplasia Prudent diet Chi-Square Distribution business.industry Papillomavirus Infections Feeding Behavior Protective Factors Uterine Cervical Dysplasia medicine.disease Case-Control Studies Cross-Sectional Studies Linear Models Logistic Models Neoplasm Grading Principal Component Analysis Risk Reduction Behavior Food Science Diet business |
| Zdroj: | Nutrients, Vol 10, Iss 4, p 469 (2018) Nutrients Nutrients; Volume 10; Issue 4; Pages: 469 |
| Popis: | Specific foods and nutrients help prevent the progression of persistent high-risk human papillomavirus (hrHPV) infection to cervical cancer (CC). The aim of this study was to investigate dietary patterns which may be associated with hrHPV status and the risk of high-grade cervical intraepithelial neoplasia (CIN2+). Overall, 539 eligible women, including 127 with CIN2+, were enrolled in a cross-sectional study, and tested for hrHPV infection. Food intake was estimated using a food frequency questionnaire. Logistic regression models were applied. Using the Mediterranean Diet Score, we demonstrated that, among 252 women with a normal cervical epithelium, medium adherence to the Mediterranean diet decreased the odds of hrHPV infection when compared to low adherence (adjOR = 0.40, 95%CI = 0.22–0.73). Using the principal component analysis, we also identified two dietary patterns which explained 14.31% of the variance in food groups intake. Women in the third and fourth quartiles of the “Western pattern” had higher odds of hrHPV infection when compared with first quartile (adjOR = 1.77, 95% CI = 1.04–3.54 and adjOR = 1.97, 95%CI = 1.14–4.18, respectively). Adjusting for hrHPV status and age, women in the third quartile of the “prudent pattern” had lower odds of CIN2+ when compared with those in the first quartile (OR = 0.50, 95%CI = 0.26–0.98). Our study is the first to demonstrate the association of dietary patterns with hrHPV infection and CC and discourages unhealthy habits in favour of a Mediterranean-like diet. |
| Databáze: | OpenAIRE |
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