Fatigue, anxiety and depression overrule the role of oncological treatment in predicting self-reported health complaints in women with breast cancer compared to healthy controls
| Autor: | Hege R. Eriksen, Ragna Lind, Håvard Søiland, Turid Aas, Jan Terje Kvaløy, Kari Britt Hagen |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Visual analogue scale Health Status Breast Neoplasms Anxiety Hospital Anxiety and Depression Scale 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Surveys and Questionnaires medicine Humans 030212 general & internal medicine Depression (differential diagnoses) Fatigue Aged Psychiatric Status Rating Scales business.industry Depression Estrogen Replacement Therapy Case-control study Cancer General Medicine Middle Aged medicine.disease Irritable Mood Postmenopause 030220 oncology & carcinogenesis Case-Control Studies Hot Flashes Physical therapy Surgery Female medicine.symptom business Tamoxifen medicine.drug |
| Zdroj: | Breast (Edinburgh, Scotland). 28 |
| ISSN: | 1532-3080 |
| Popis: | Women with breast cancer often attribute their health problems as side effects caused by oncological treatments. The aim of the study was to examine and compare self-reported health complaints (SHC) in postmenopausal patients with breast cancer to healthy controls.Women with breast cancer (N = 196) filled in 5 questionnaires 1-2 years after surgery; SHC Inventory, Functional Assessment of Cancer Therapy-Endocrine Subscale (FACT-ES), Fatigue - Functional Assessment of Cancer Therapy-Fatigue subscale (FACIT-F), Fatigue Visual Analog Scale (Fatigue VAS), and Hospital Anxiety and Depression Scale (HADS). Controls comprised 101 blood donors who reported on the questionnaires except for HADS. Bonferroni adjustment and p 0.0017 was considered statistically significant for SHC Inventory, p 0.05 for the remaining questionnaires.The patients, mean age 58.0 (SD 9.5), reported significantly more self-reported health complaints, whereof 6 of 29 complaints were significantly elevated compared to the controls, mean age 57.0 (SD 5.8) (p 0.001). HADS scores in patients fell into normal range, mean 6.3 (SD 5.7). A subgroup of 48 patients experienced more frequent and severe symptoms in all the questionnaires compared to the remaining 148 patients, and the 101 controls. Among the patients, fatigue, anxiety and depression explained 49% of the total variance in self-reported health complaints (p ≤ 0.001).Most women with breast cancer (76%) reported health complaints equal to the healthy controls. Fatigue, anxiety and depression, not oncological treatments, were significant predictors for the complaints. |
| Databáze: | OpenAIRE |
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