Single-dose oral cefixime versus amoxicillin plus probenecid for the treatment of uncomplicated gonorrhea in men
| Autor: | W R Bowie, V Willetts, K Lefebvre, D W Megran |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.drug_class Gonorrhea Antibiotics Cefotaxime urologic and male genital diseases medicine.disease_cause Gastroenterology Cefixime Internal medicine medicine Humans Pharmacology (medical) Urethritis Randomized Controlled Trials as Topic Pharmacology Probenecid business.industry Amoxicillin medicine.disease female genital diseases and pregnancy complications Surgery Infectious Diseases business Chlamydia trachomatis Research Article medicine.drug Ureaplasma urealyticum |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 34:355-357 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.34.2.355 |
| Popis: | In this randomized study, a single 800-mg oral dose of cefixime cured 96 of 97 men with uncomplicated gonococcal urethritis, compared with 44 cures of 46 men who received standard therapy with amoxicillin (3 g) plus probenecid (1 g). Both regimens were ineffective against coexistent infection with Chlamydia trachomatis and Ureaplasma urealyticum. Cefixime was well tolerated, and all side effects were mild and self-limited. |
| Databáze: | OpenAIRE |
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