Prevalence of and mothers' knowledge, attitude and practice towards glucose-6-phosphate dehydrogenase deficiency among neonates with jaundice: a cross-sectional study
| Autor: | Sally M El Hefnawy, Safa H Alkalash, Zeinab A Kasemy, Wael A Bahbah |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Health Knowledge Attitudes Practice Cross-sectional study Mothers Consanguinity family medicine Risk Factors hemic and lymphatic diseases Epidemiology parasitic diseases medicine Odds Ratio Prevalence Humans Family history business.industry Public health Infant Newborn nutritional and metabolic diseases General Medicine Jaundice medicine.disease Jaundice Neonatal Cross-Sectional Studies Glucosephosphate Dehydrogenase Deficiency Medicine Health education Egypt Female epidemiology Public Health medicine.symptom business community child health Glucose-6-phosphate dehydrogenase deficiency G6PD |
| Zdroj: | BMJ Open BMJ Open, Vol 10, Iss 2 (2020) |
| ISSN: | 2044-6055 |
| Popis: | BackgroundNeonatal jaundice (NNJ) is a frequent complication of glucose-6-phosphate dehydrogenase (G6PD) deficiency.ObjectivesTo estimate the prevalence of G6PD deficiency among neonates with jaundice and to assess mothers’ perception towards G6PD and NNJ.MethodsA cross-sectional study was carried out on 487 ethnic Egyptian neonates with indirect hyperbilirubinaemia from June 2018 to July 2019. The collected data included maternal and neonatal characteristics. Laboratory investigations included serum bilirubin, reticulocyte count, ABO grouping, Rh typing and neonatal serum G6PD test. Mothers were interviewed individually using a structured, researcher-administered questionnaire to assess their perceptions of G6PD deficiency and NNJ.ResultsThe prevalence of G6PD deficiency was 10.10%. Neonates with G6PD deficiency showed higher levels of serum bilirubin (pConclusionG6PD deficiency seems to be an important cause of NNJ. Mothers’ perceptions of both NNJ and G6PD deficiency were low. A mass health education programme on both of these diseases is needed to ensure better and early detection, good timing of treatment, and better prevention of the triggering factors to ensure better health for children. |
| Databáze: | OpenAIRE |
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