Manual morphometry of hippocampus and amygdala in adults with attention-deficit hyperactivity disorder
| Autor: | Daniel Beier, Peter Goll, Dominique Endres, Ludger Tebartz van Elst, Renate Jitten-Schachenmeier, Evgeniy Perlov, Simon Maier, Kathrin Nickel, Alexandra Philipsen |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Left amygdala Neuroscience (miscellaneous) Hippocampus behavioral disciplines and activities Amygdala 03 medical and health sciences Young Adult 0302 clinical medicine mental disorders medicine Attention deficit hyperactivity disorder Humans Radiology Nuclear Medicine and imaging medicine.diagnostic_test Magnetic resonance imaging Organ Size Middle Aged medicine.disease Magnetic Resonance Imaging 030227 psychiatry Psychiatry and Mental health medicine.anatomical_structure nervous system Attention Deficit Disorder with Hyperactivity Case-Control Studies Female Psychology Neuroscience psychological phenomena and processes 030217 neurology & neurosurgery |
| Zdroj: | Psychiatry research. Neuroimaging. 267 |
| ISSN: | 1872-7506 |
| Popis: | Previous studies have pointed to the involvement of limbic structures in the genesis of attention deficit hyperactivity disorder (ADHD). The present researchers manually segmented magnetic resonance images of 30 individuals with ADHD and 30 individually matched controls, focusing on amygdala and hippocampus volumes. Neither hippocampus nor amygdala volume differed significantly between individuals with and without ADHD. However, ADHD patients with higher hyperactivity scores had significantly smaller left amygdala volumes. This finding suggests that limbic alterations are significant in hyperactive symptoms in the pathophysiology of ADHD. |
| Databáze: | OpenAIRE |
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