Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis
Autor: | Mudit Chowdhary, Devon Tobey, Thomas D Hope, Ahmad A Kabbani |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
focal segmental glomerulosclerosis
medicine.medical_specialty posterior reversible encephalopathy syndrome Subarachnoid hemorrhage medicine.diagnostic_test business.industry subarachnoid hemorrhage Neurotoxicity Magnetic resonance imaging Posterior reversible encephalopathy syndrome Case Report Disease medicine.disease PRES Surgery Focal segmental glomerulosclerosis Internal medicine Cardiology Medicine business Nephrotic syndrome Kidney disease |
Zdroj: | Neuropsychiatric Disease and Treatment |
ISSN: | 1178-2021 1176-6328 |
Popis: | Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome characterized by reversible vasogenic edema in the posterior hemispheres. PRES is most often attributed to primary hypertension, pre-eclampsia, and neurotoxicity secondary to immunosuppressants such as cyclosporine. Renal disease is an infrequent cause of PRES with a majority of cases occurring in adults with complete renal failure or in pediatric cases with underlying renal parenchymal disease and concurrent immunosuppressive therapy. Typical symptoms include seizure, headache, altered mental status, and visual disturbances. PRES is rarely associated with cerebral hemorrhage, and even less so with subarachnoid bleeds. Herein we report on a 25-year-old female with focal segmental glomerulosclerosis who developed PRES. The patient’s presentation was more severe as she presented with seizure, nephrotic syndrome, and subarachnoid hemorrhage. Computed tomography and magnetic resonance imaging with concurrent symptoms led us to the final diagnosis. The patient was treated with antihypertensives, diuretics, and corticosteroids and follow-up imaging revealed resolution of PRES. Our case illustrates that underlying kidney disease even without immunosuppressive agents should be added to the list of possible causes for PRES. Symptoms are reversible with treatment of underlying cause or offending agent. |
Databáze: | OpenAIRE |
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