Chemical composition, antioxidant activity and larvicidal effects of essential oil from leaves of Apium graveolens
| Autor: | Sun-Jin Kim, Ateeque Ahmad, Ill-Min Chung, Praveen Nagella |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Antioxidant
DPPH medicine.medical_treatment Immunology Toxicology Antioxidants law.invention chemistry.chemical_compound Inhibitory Concentration 50 Picrates law Aedes Botany medicine Oils Volatile Immunology and Allergy Animals Hydroxymethyl Food science Organic Chemicals Essential oil Apium Pharmacology Chemistry Biphenyl Compounds Apium graveolens General Medicine Free Radical Scavengers Biphenyl compound Plant Leaves Larva Composition (visual arts) Gas chromatography |
| Zdroj: | Immunopharmacology and immunotoxicology. 34(2) |
| ISSN: | 1532-2513 |
| Popis: | The leaves of Apium graveolens were extracted and the essential oil composition, immunotoxicity effects, and antioxidant activity were studied. The analyses were conducted by gas chromatography and mass spectroscopy (GC-MS), which revealed the essential oils of A. graveolens leaves. Twenty-eight components, representing 73.72% of the total oil were identified from the leaves. The major components are 4-chloro-4,4-dimethyl-3-(1-imidazolyl)-valerophenone (19.90%), 1-dodecanol (16.55%), 9-octadecen-12-ynoic acid, methyl ester (4.93%), ethyl 4,4-D2-N-hexyl ether (4.11%), 3-(hydroxymethyl)-1-phenyl-1-heptadecyn-3-ol (3.28%), 1,4-methano-1H-indene, octahydro-4-methyl-8-methylene-7-(1-methylethyl)-, [1S-(1α,3αα,4α,7α,7αα)]- (2.99%), 3,4-dihydro-2H-1,5-(3″-t-butyl)benzodioxepine (2.56%), Z-10-tetradecen-1-ol acetate (2.53%), 9H-pyrrolo[3',4':3,4]pyrrolo[2,1-α]phthalazine-9, 11(10H)-dione, 10-ethyl-8-phenyl (2.07%). The leaf oil had significant toxic effects against the larvae of A. aegypti with an LC(50) value of 59.32 ppm and an LC(90) value of 127.69 ppm. The essential oil from the A. graveolens leaves was investigated for scavenging of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical activity and the results demonstrate that the essential oil from the A. graveolens has potential as a natural antioxidant and thus inhibit unwanted oxidation process. The above data indicate that the major compounds may play an important role in the toxicity of essential oils and also as natural antioxidant. |
| Databáze: | OpenAIRE |
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