Sensory and descending motor circuitry during development and injury
| Autor: | Julia A. Kaltschmidt, Giles W. Plant, Jarret A.P. Weinrich |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Proprioception General Neuroscience Sensory system Biology medicine.disease Article 03 medical and health sciences Sensory input Neurons Efferent 030104 developmental biology 0302 clinical medicine Spinal Cord Interneurons medicine Animals Humans Neurons Afferent Nerve Net Neuroscience Spinal cord injury Locomotion Spinal Cord Injuries 030217 neurology & neurosurgery |
| Zdroj: | Current Opinion in Neurobiology. 53:156-161 |
| ISSN: | 0959-4388 |
| DOI: | 10.1016/j.conb.2018.08.008 |
| Popis: | Proprioceptive sensory input and descending supraspinal projections are two major inputs that feed into and influence spinal circuitry and locomotor behaviors. Here we review their influence on each other during development and after spinal cord injury. We highlight developmental mechanisms of circuit formation as they relate to the sensory-motor circuit and its reciprocal interactions with local spinal interneurons, as well as competitive interactions between proprioceptive and descending supraspinal inputs in the setting of spinal cord injury. |
| Databáze: | OpenAIRE |
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