The Effect of Trabeculae Carneae on Left Ventricular Diastolic Compliance: Improvement in Compliance With Trabecular Cutting
| Autor: | Hai Chao Han, Marc D. Feldman, Joel E. Michalek, Pedro J. Acevedo, Daniel Escobedo, David L. Halaney, Arnav Sanyal, Navid A. Nafissi, Martin Goros, G. Patricia Escobar, William Pérez |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Heart Ventricles Biomedical Engineering Diastole 030204 cardiovascular system & hematology Ventricular Function Left 03 medical and health sciences Wall stress 0302 clinical medicine Physiology (medical) Internal medicine medicine Humans 030212 general & internal medicine LV hypertrophy Aged Trabeculae carneae business.industry Myocardium Models Cardiovascular Human heart Structural engineering Middle Aged Research Papers Compliance (physiology) medicine.anatomical_structure Cardiology Female Stress Mechanical business |
| Zdroj: | Journal of Biomechanical Engineering. 139 |
| ISSN: | 1528-8951 0148-0731 |
| Popis: | The role of trabeculae carneae in modulating left ventricular (LV) diastolic compliance remains unclear. The objective of this study was to determine the contribution of trabeculae carneae to the LV diastolic compliance. LV pressure–volume compliance curves were measured in six human heart explants from patients with LV hypertrophy at baseline and following trabecular cutting. The effect of trabecular cutting was also analyzed with finite-element model (FEM) simulations. Our results demonstrated that LV compliance improved after trabecular cutting (p |
| Databáze: | OpenAIRE |
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