The efficacy of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis
| Autor: | Cao Yang, Wenbin Hua, Xianlin Zeng, Wencan Ke, Yukun Zhang, Bingjin Wang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Posterior approach medicine.medical_specialty Tuberculosis Visual analogue scale Kyphosis lcsh:Surgery Thoracic Vertebrae Young Adult 03 medical and health sciences 0302 clinical medicine Allograft Thoracic and thoracolumbar Humans Medicine Surgical treatment Aged Retrospective Studies Titanium 030222 orthopedics Bone Transplantation Cobb angle medicine.diagnostic_test business.industry Allograft bone General Medicine lcsh:RD1-811 Middle Aged Plastic Surgery Procedures Surgical Mesh medicine.disease Oswestry Disability Index Surgery Titanium mesh Radiography Spinal Fusion Treatment Outcome Debridement Erythrocyte sedimentation rate Spinal tuberculosis Female Tuberculosis Spinal Tomography X-Ray Computed business 030217 neurology & neurosurgery Research Article |
| Zdroj: | BMC Surgery, Vol 20, Iss 1, Pp 1-7 (2020) BMC Surgery |
| DOI: | 10.21203/rs.2.14957/v1 |
| Popis: | Background The bony fusion of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis has not been explained in detail. We aimed to analyze the efficacy of bony fusion of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis. Methods We treated 32 thoracic or thoracolumbar tuberculosis patients by one-stage posterior debridement, allograft bone graft using titanium mesh, posterior instrumentation, and fusion from May 2011 to September 2015. The American Spinal Injury Association neurological classification, visual analog scale, and Oswestry disability index scores were analyzed preoperatively, postoperatively, and at final follow-up. The Cobb angles were recorded to evaluate the kyphosis correction and the loss of correction. The bony fusion was evaluated by X-ray and computed tomography images, and the bony fusion classifications were recorded. Results All patients had pain relief. The erythrocyte sedimentation rate, C-response protein, and hepatorenal function were normal at final follow-up. The American Spinal Injury Association neurological classification, visual analog scale, and Oswestry disability index scores were improved in all the patients. All patients achieved bone fusion. Twenty-eight patients achieved complete fusion (Grade I), whereas only four patients achieved partial fusion (Grade II). The preoperative Cobb angle was 33.6 ± 9.3°. The Cobb angle was reduced to 10.6 ± 2.6° postoperatively and was found to be 11.4 ± 3.1° at the final follow-up. The mean angle correction was 23.0 ± 8.9°, and the correction rate was 66.2 ± 12.2%. The mean angle lost was 0.8 ± 0.9°, and the lost rate was 5.8 ± 5.4% at the final follow-up. Conclusions Allograft bone using titanium mesh in the posterior-only surgical treatment is effective for patients with thoracic and thoracolumbar spinal tuberculosis. It can correct kyphosis, and most patients can achieve complete bony fusion. |
| Databáze: | OpenAIRE |
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