Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET

Autor: Tanem, Kristine Eidal, Stensvold, Einar, Wilberg, Petter, Skaare, Anne B, Singh, Preet Bano, Brandal, Petter, Herlofson, Bente Brokstad
Rok vydání: 2021
Předmět:
Zdroj: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 30(7)
ISSN: 1433-7339
0941-4355
Popis: Purpose To investigate taste and smell function in survivors, with a minimum of 2 years since treatment of childhood medulloblastoma (MB)/central nervous system supratentorial primitive neuroectodermal tumor (CNS-PNET). Methods This cross-sectional study included 40 survivors treated ≤ 20 years of age. Taste strips with four concentrations of sweet, sour, salt, and bitter were used to assess taste function in all participants. Score from 0 to 16; ≥ 9 normogeusia, 16.00– Results Forty survivors with a mean time since treatment of 20.5 years, 13 (32.5%) were diagnosed with hypogeusia, nine (22.5%) of these being ageusic to one or more taste qualities. Seventeen (53%) of 32 participants were diagnosed with hyposmia. The mean scores of the olfactory subtests, and TDI score were significantly lower than normative data (P Conclusion Our study showed impaired taste and smell function in survivors of childhood MB/CNS-PNET using objective measurements. However, subjective ratings did not reflect objective findings.
Databáze: OpenAIRE
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