Stimulus-Responsive Metal–Organic Framework Signal-Reporting System for Photoelectrochemical and Fluorescent Dual-Mode Detection of ATP

Autor: Li Zhang, Feng-Zao Chen, Haodi Sun, Runze Meng, Qingsheng Zeng, Xinxing Wang, Hong Zhou
Rok vydání: 2022
Předmět:
Zdroj: ACS Applied Materials & Interfaces. 14:46103-46111
ISSN: 1944-8252
1944-8244
DOI: 10.1021/acsami.2c14376
Popis: Dual-mode bioanalysis integrating photoelectrochemical (PEC) and other modes is emerging and allows signal cross-checking for more reliable results. Metal-organic frameworks (MOFs) have been shown to be attractive materials in various biological applications. This work presents the utilization of MOF encapsulation and stimuli-responsive decapsulation for dual-mode PEC and fluorescence (FL) bioanalysis. Photoactive dye methylene violet (MV) was encapsulated in zeolitic imidazolate framework-90 (ZIF-90) to form an MV@ZIF-90 hybrid material, and MV could be released by adenosine triphosphate (ATP)-induced ZIF-90 disintegration. The released MV not only had FL emission but also had a sensitization effect on the ZnIn
Databáze: OpenAIRE