The prevention of rabbit atherosclerosis by soya bean meal
| Autor: | G.A. Gresham, A.N. Howard, I.W. Jennings, D. Jones |
|---|---|
| Rok vydání: | 1965 |
| Předmět: |
Vitamin
Meal Arteriosclerosis Diet therapy Research Hypercholesterolemia digestive oral and skin physiology food and beverages General Medicine Atherosclerosis Lipids Bone meal Diet chemistry.chemical_compound Bone ash chemistry Tallow Casein Animals Rabbits Soybeans Food science Corn oil Diet Therapy |
| Zdroj: | Journal of Atherosclerosis Research. 5:330-337 |
| ISSN: | 0368-1319 |
| DOI: | 10.1016/s0368-1319(65)80048-5 |
| Popis: | Summary Groups of rabbits were given an atherogenic diet containing 20 % beef tallow for 16 weeks and the aortae examined macroscopically after staining with Sudan. Variations of this diet were made by replacing various constituents by other “natural products”. Substitution of beef tallow by corn oil prevented the hypercholesterol-aemia but not the arterial lesions, although they were less severe. Replacement of the vitamin mixture by yeast and cabbage, corn starch by corn meal, mineral mix by bone meal or bone ash and casein by purified soya bean proteins did not effect the aortic atherosclerosis or hypercholesterolaemia. However, replacement of casein by whole soya flour and hexane-extracted soya bean meal was more effective in preventing the disease. It is suggested that the rabbit natural diet contains a nutrient which prevents atherosclerosis and which is also present in extracted soya bean meal. Preliminary attempts to isolate this factor show that it is not purified soya protein, phospholipid or triglyceride. It is unlikely the disease is caused by a toxic factor since no one constituent was essential and also rabbits given a mixture of natural diets and atherogenic diet did not have the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|