Variability of the Expression of Reference Genes in Samples of Human Olfactory Epithelium

Autor:	Lyubomir I. Aftanas, A. S. Avdeeva, N. S. Rudenko, K. V. Danilenko, S. P. Kovalenko
Rok vydání:	2018
Předmět:	Adult Male 0301 basic medicine Hypoxanthine Phosphoribosyltransferase Adolescent Biopsy In Vitro Techniques Biology General Biochemistry Genetics and Molecular Biology Young Adult 03 medical and health sciences 0302 clinical medicine Olfactory Mucosa Reference genes Gene expression Healthy volunteers medicine Humans Gene medicine.diagnostic_test Gene Expression Profiling Nuclear Proteins RNA-Binding Proteins General Medicine Middle Aged Molecular biology Neoplasm Proteins Gene Expression Regulation Neoplastic 030104 developmental biology medicine.anatomical_structure Expression (architecture) Female Olfactory epithelium 030217 neurology & neurosurgery
Zdroj:	Bulletin of Experimental Biology and Medicine. 164:655-657
ISSN:	1573-8221 0007-4888
DOI:	10.1007/s10517-018-4052-7
Popis:	We analyzed variability of the expression of three reference genes in biopsy samples of the olfactory epithelium obtained from healthy volunteers. The expression of B2M, HPRT1, and CASC3 genes was analyzed by real-time PCR. The pairs of genes B2M-HPRT1 and B2M-CASC3 were found to possess minimum individual variability of expression and can be reliable candidates for the reference genes in analysis of gene expression in neural cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6b3c21d2980991bbec6182a7c8ca6f https://doi.org/10.1007/s10517-018-4052-7 Zobrazit plný text záznamu Full text from SpringerLink