Blood cells and their effect on the lipid profile in women with essential hypertension
| Autor: | B. I. Kuznik, E. S. Guseva, S. O. Davydov, Yu. N. Smolyakov, E. V. Roitman, N. N. Tsybikov |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Very low-density lipoprotein hypertension 030204 cardiovascular system & hematology Stage ii Essential hypertension lipids 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine correlations Internal medicine medicine Diseases of the circulatory (Cardiovascular) system Platelet Kinesiotherapy kinesiotherapy Triglyceride business.industry Lipid metabolism medicine.disease 030104 developmental biology Endocrinology chemistry RC666-701 Correlation analysis blood cells Cardiology and Cardiovascular Medicine business |
| Zdroj: | Российский кардиологический журнал, Vol 25, Iss 3 (2020) |
| ISSN: | 2618-7620 1560-4071 |
| Popis: | Aim.To find out the relationship of particular blood cells (BC) and their ratios with lipid metabolism in patients with essential hypertension (EH), with (EH-1) and without kinesiotherapy (EH-2).Material and methods.The study included 30 healthy women (control group) and 72 women with EH, which were divided into 2 groups: group 1 (EH-1) — 37 women with stage II (target organ damage classification) hypertension who receive antihypertensive therapy; group 2 (EH-2) — 35 women who underwent antihypertensive therapy and kinesiotherapy (3-4 courses for 2-3 years).Results.Correlation analysis revealed that the studied relationships in healthy women, EH-1 and EH-2 women can be either direct or inverse. In healthy women, we observed negative association of monocytes (MON) with atherogenic index (AI), a positive association of basophils (BAS) with high density lipoproteins (HDL) and its negative association with low density lipoproteins (LDL), very low density lipoproteins (VLDL) and AI and red blood cells/platelets (RBC/PLT ratio) with HDL. Negative associations of lymphocytes (LYM)/BAS ratio with triglyceride (TG) and eosinophils (EOS)/BAS ratio with LDL were also detected. Patients with EH-1 had a direct relationship between LYM/EOS ratio and TG. In patients with EH-2, a negative relationship was found between PLT and HDL, MON and HDL, neutrophils (NEU)/MON ratio and TAG, and a positive — between white blood cells (WBC), NEU, MON and AI, LYM and TAG, MON and TAG, as well as AI.Conclusion.The obtained data indicate that all BC and their ratios in women with/without EH and with/without kinesiotherapy affect the lipid metabolism. |
| Databáze: | OpenAIRE |
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