Usefulness of repeated fine-needle cytology in the follow-up of non-operated thyroid nodules
| Autor: | Frédéric, Illouz, Patrice, Rodien, Jean Paul, Saint-André, Stéphane, Triau, Sandrine, Laboureau-Soares, Séverine, Dubois, Bruno, Vielle, Antoine, Hamy, Hamy, Antoine, Vincent, Rohmer |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Thyroid nodules medicine.medical_specialty Cytodiagnosis Endocrinology Diabetes and Metabolism Biopsy Fine-Needle Thyroid Gland Diagnosis Differential Endocrinology Internal medicine Cytology Biopsy medicine Humans Thyroid Neoplasms Retrospective Studies medicine.diagnostic_test business.industry Follow up studies Reproducibility of Results Nodule (medicine) General Medicine Middle Aged medicine.disease Female Radiology medicine.symptom business Follow-Up Studies Endocrinology department |
| Zdroj: | European Journal of Endocrinology. 156:303-308 |
| ISSN: | 1479-683X 0804-4643 |
| DOI: | 10.1530/eje-06-0616 |
| Popis: | Objective: The usefulness of repeated fine-needle cytology (FNC) in thyroid nodules with benign cytology remains unknown. We analyzed the relevance of repeated FNC to detect suspicious or malignant (S/M) cytologies and carcinomas. Design: A retrospective study (1983–2004) was conducted in our endocrinology department. Methods: We reviewed the reports of 895 adequate FNC performed in 298 patients (298 nodules) during a mean follow-up of 5 years. We compared the nodules with at least one suspicious or malignant FNC (S/M nodules) with nodules with repeatedly benign (RB) FNC (RB nodules). Results: Among the nodules with initial benign cytology, we found 35 nodules with one or more later suspicious or malignant results. The interval between the first FNC and the first S/M FNC was 2.9 years. The probability for a nodule to have a repeated benign FNC decreases with time and with the number of FNC. We did not find any clinical or ultrasonographic characteristics related to an S/M cytology. Seven cancers were detected by the second or the third FNC with S/M results. The proportion of cancers among S/M nodules was similar when S/M cytology appears during the first, the second, or the third FNC. Conclusions: We suggest to repeat FNC up to three adequate samples in the follow-up of thyroid nodules so as not to miss the presence of malignant neoplasm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|