Bin/Amphiphysin/Rvs (BAR) Family Members Bend Membranes in Cells
| Autor: | Allison Suarez, Takanari Inoue, J. Michael McCaffery, Tasuku Ueno, Robert Huebner |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Multidisciplinary
COS cells Bar (music) Cell Membrane Biophysics Nerve Tissue Proteins Biology Article Bin Cell Line Cell biology Cell membrane Structure-Activity Relationship Membrane medicine.anatomical_structure Membrane curvature COS Cells Chlorocebus aethiops Organelle Amphiphysin medicine Animals lipids (amino acids peptides and proteins) |
| Zdroj: | Scientific Reports |
| ISSN: | 0006-3495 |
| DOI: | 10.1016/j.bpj.2014.11.1353 |
| Popis: | We provide direct evidence that Bin/Amphiphysin/Rvs (BAR) family members bend the steady state membrane architecture of organelles in intact cells. In response to inducible BAR molecular actuators, organelles exhibit distinct changes to the orientation and degree of their membrane curvature. This rapidly inducible system may offer a mechanism by which to better understand the structure-function relationship of intracellular organelles. |
| Databáze: | OpenAIRE |
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