Reserpine and breast cancer
| Autor: | Nancy McCarthy, Dankward Kodlin |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Gynecology
Cancer Research medicine.medical_specialty Reserpine Time Factors business.industry Obstetrics Statistics as Topic Age Factors Breast Neoplasms medicine.disease Causality Medical care Breast cancer Oncology Hypertension Humans Medicine Female Hypertension diagnosis Epidemiologic Methods business Aged medicine.drug |
| Zdroj: | Cancer. 41:761-768 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(197802)41:2<761::aid-cncr2820410250>3.0.co;2-2 |
| Popis: | After a series of studies on the linkage of reserpine with breast cancer, both evidence and interpretation appeared to be in conflict. Our case-control survey of long-term, comprehensive records from the Kaiser Foundation Medical Care Program, on 108 hypertensive breast cancer cases and 324 hypertensive controls, matched by year of birth and by race, produces a significant positive association between reserpine use and breast cancer. However, the association vanishes upon further matching with respect to the year of the first hypertension diagnosis and the subsequent length of follow-up. We thus fail to support suspicions of causality. |
| Databáze: | OpenAIRE |
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