Presence of elevated circulating levels of LH during the pre-menstrual period in some copper IUD users and the possibility of their confusion with hCG
| Autor: | Katayun Virkar, Anil R. Sheth, J.V. Joshi, B. Dattatreyamurty, S. Mehta |
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| Rok vydání: | 1979 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty media_common.quotation_subject Radioimmunoassay Chorionic Gonadotropin Menstruation Radioligand Assay Menstrual period Internal medicine medicine Humans Endocrine system reproductive and urinary physiology Menstrual cycle media_common Confusion urogenital system business.industry Obstetrics and Gynecology Luteinizing Hormone Intrauterine Devices Copper Endocrinology Reproductive Medicine Female medicine.symptom business Luteinizing hormone hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Contraception. 19:213-221 |
| ISSN: | 0010-7824 |
| DOI: | 10.1016/0010-7824(79)90015-5 |
| Popis: | A heterologous radioimmunoassay (RIA) capable of discriminating between LH and hCG was used to measure LH levels in sera obtained during the pre- and post-menstrual periods from 80 women bearing copper intrauterine contraceptive devices (IUD). hCG levels in these samples were also estimated by use of a homologous beta-hCG radioimmunoassay and a radioligand-receptor assay. Only two IUD users during the pre-menstrual period had detectable, but low hCG levels. However, LH levels, as estimated by specific RIA, in the serum of these two women were elevated to a level that would cause detection at low levels in the hCG assays. The data thus provide direct evidence to indicate that the positive hCG levels observed by others during the pre-menstrual period in some copper IUD users could be due to the interference in hCG assays by elevated LH. |
| Databáze: | OpenAIRE |
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