Chemically Modifying Viruses for Diverse Applications
| Autor: | Gregory A. Weiss, Kritika Mohan |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Bioelectric Energy Sources
viruses Nanotechnology 02 engineering and technology Biosensing Techniques 010402 general chemistry Regenerative Medicine 01 natural sciences Biochemistry Article Drug Delivery Systems Biomimetics Animals Humans Bacteriophages Reaction conditions Chemistry Extramural Organic Chemistry General Medicine Biological Sciences 021001 nanoscience & nanotechnology 0104 chemical sciences Generic Health Relevance Drug delivery Viruses Chemical Sciences Molecular Medicine 0210 nano-technology Genetic Engineering Biosensor |
| Zdroj: | ACS chemical biology, vol 11, iss 5 Mohan, K; & Weiss, GA. (2016). Chemically Modifying Viruses for Diverse Applications. ACS CHEMICAL BIOLOGY, 11(5), 1167-1179. doi: 10.1021/acschembio.6b00060. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/94v7n80n |
| DOI: | 10.1021/acschembio.6b00060. |
| Popis: | Long fascinating to biologists, viruses offer nanometer-scale benchtops for building molecular-scale devices and materials. Viruses tolerate a wide-range of chemical modifications including reaction conditions, pH values, and temperatures. Recent examples of non-genetic manipulation of viral surfaces have extended viruses into applications ranging from biomedical imaging, drug delivery, tissue regeneration, and biosensors to materials for catalysis and energy generation. Chemical reactions on the phage surface include both covalent and non-covalent modifications, including some applied in conjunction with genetic modifications. Here, we survey viruses chemically augmented with capabilities limited only by imagination. |
| Databáze: | OpenAIRE |
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