Polimorfizam beta-kazeinskog gena i njegova povezanost sa karakteristikama za mleko kod holštajnfrizijskih krava iz Srbije
Autor: | Kirovski Danijela, Teodorovic Vlado, Ristanić Marko, Maletic Milan, Glavinic Uros, Stanimirović Zoran, Vejnović Branislav |
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Rok vydání: | 2020 |
Předmět: |
RFLP-PCR
Holstein-Friesian 030309 nutrition & dietetics Veterinary medicine Biology 03 medical and health sciences Animal science Casein SF600-1100 milk productivity traits Beta (finance) holstein-friesian 2. Zero hunger 0303 health sciences General Veterinary 0402 animal and dairy science food and beverages 04 agricultural and veterinary sciences beta-casein Milk production rflp-pcr 040201 dairy & animal science 3. Good health Gene polymorphism genotype frequency allele frequency |
Zdroj: | Acta Veterinaria, Vol 70, Iss 4, Pp 497-510 (2020) Acta Veterinaria-Beograd |
ISSN: | 1820-7448 |
DOI: | 10.2478/acve-2020-0037 |
Popis: | The most common types of beta-casein in cow’s milk are A1 and A2, which differ in one amino acid. During the gastrointestinal proteolysis of A1 beta-casein in humans this difference results in the release of beta-casomorphin-7, an opioid which may lead to severe effects on human health, causing various ailments (type-1 diabetes mellitus, ischemic heart disease, arteriosclerosis, sudden infant death syndrome, autism, schizophrenia, gastrointestinal digestive discomfort, as well as increased gastrointestinal transit time). By contrast, A2 beta-casein cannot exert these effects owing to its different composition and metabolism. Furthermore, studies have shown that it can influence milk productivity traits. Our research aimed to screen the frequency of A1 and A2 alleles of beta-casein gene in a population of Serbian Holstein-Friesian cows and to detect how the genotypes influence milk production, and milk protein and fat yields. Out of 106 animals, 13 (12.26%) were of A1A1 genotype, 58 (54.72%) of A1A2, and 35 (33.02%) of A2A2 genotype. Milk yield was significantly (P |
Databáze: | OpenAIRE |
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