Neuropsychological performance of right- and left-frontotemporal dementia compared to Alzheimer's disease
| Autor: | Bruce L. Miller, Kyle B. Boone, Jill Razani, Dale Sherman, Alison Lee |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Apraxias Neuropsychological Tests Audiology Severity of Illness Index Functional Laterality Perceptual Disorders Nonverbal communication Fluency Alzheimer Disease mental disorders Severity of illness medicine Humans Dementia Semantic memory Language Disorders Memory Disorders business.industry General Neuroscience Neuropsychology Cognition Middle Aged medicine.disease Temporal Lobe Frontal Lobe Psychiatry and Mental health Clinical Psychology Visual Perception Female Neurology (clinical) Cognition Disorders business Frontotemporal dementia |
| Zdroj: | Journal of the International Neuropsychological Society. 7:468-480 |
| ISSN: | 1469-7661 1355-6177 |
| DOI: | 10.1017/s1355617701744037 |
| Popis: | The performance of 16 patients with Alzheimer's disease (AD) was compared to 11 patients with right-frontotemporal dementia (FTD) and 11 patients with left-FTD on a comprehensive neuropsychological battery. Standardized scores (i.e., z scores based on normal control data) were analyzed for 5 cognitive domains. The results revealed that the AD group displayed significant impairment in visual–constructional ability relative to the two FTD groups; however, no significant difference was found between the groups on memory scores (verbal and nonverbal). Patients with left-FTD scored significantly below patients with AD on the language measures (e.g., word retrieval, verbal semantic memory), and verbal executive ability (phonemic fluency); AD patients did not differ from patients with right-FTD on these measures. Patients with right-FTD exhibited significantly more perseverative behavior than AD patients; AD patients did not differ from left-FTD patients on this parameter. These results indicate that the pattern of neuropsychological performance of AD patients is distinguishable from patients with left and right frontal frontotemporal dementia. (JINS, 2001, 7, 468–480) |
| Databáze: | OpenAIRE |
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