Metabolism of phenylalanine, tyrosine and aspartic acid in growing rats at various dietary protein levels

Autor:	Masaji Ogura, Yasuo Nakatomi, Hideyuki Tanaka
Rok vydání:	1987
Předmět:	chemistry.chemical_classification Calorie Phenylalanine+Tyrosine Phenylalanine Metabolism General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound chemistry Biochemistry Carbon dioxide Aspartic acid Tyrosine General Agricultural and Biological Sciences Essential amino acid
Zdroj:	Agricultural and Biological Chemistry. 51:499-505
ISSN:	1881-1280 0002-1369
DOI:	10.1271/bbb1961.51.499
Popis:	The metabolic fate of the carbon skeleton of l-[U-14C]phenylalanine, tyrosine and aspartic acid was investigated in growing rats fed with diets containing different percentages of protein calories (0, 5, 10, 15 and 30 PC%) at 4100 kcal of metabolizable energy per kg of diet.The incorporation of 14C into the body protein at 12 hr after the injection of 14C-phenylalanine was more than 80% of the dose in the dietary groups of 0 and 5 PC%, and it decreased gradually at higher PC% levels. The pattern of incorporation of 14C-tyrosine into the body protein was similar to that of phenylalanine. The carbon skeleton of 14C-aspartic acid was extensively oxidized to expired carbon dioxide, and 14C incorporation into the body protein was markedly less. The pattern of expired 14CO2 production from each 14C-amino acid was in inverse proportion to that of 14C incorporation into the body protein.These results suggest that although tyrosine is not an essential amino acid for the growth of rats, the carbon skeleton of tyros...
Databáze:	OpenAIRE
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