Figure S1 from Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner

Autor: Hans Christian Reinhardt, Sven Perner, David Maintz, Thorsten Persigehl, Jürgen Thomale, Björn Schumacher, Reinhard Büttner, Jürgen Wolf, Martin Erkel, Michael Nowak, Mehmet Deniz Akyuz, Daniela Welcker, Alexandra Florin, Luka Ozretić, Sebastian Michels, Maike Wittersheim, Arina Riabinska, Anna Schmitt, Christian Fritz, Christiane Kümpers, Anne Offermann, Wenzel Vogel, Judith Spiro, Niklas Klümper, Miriam Rinneburger, Ignacija Vlašić, Mladen Jokić
Rok vydání: 2023
Popis: S1.(a) Distribution of tumor vs. normal lung tissue in K, KE, KP and KPE mice at 4 weeks post tumor induction (top). Distribution of murine lung adenocarcinoma grades (G1, G2, G3) in corresponding K, KE, KP and KPE mice at 4 weeks post tumor induction (bottom). (b) Anti-Ercc1 immunostaining of lung sections of KE mice (n = 2) at 4 weeks post tumor induction (mouse KE.1 shown at two magnifications, mouse KE.2 shown at two magnifications) (top). Anti-Ercc1 immunostaining of lung sections of KE mice (n = 2) at 12 weeks post tumor induction (mouse KE.3 shown at two magnifications, mouse KE.4 shown at two magnifications) (bottom). (c) Anti-Ercc1 immunostaining of lung sections of KPE mice (n = 5) at 4 weeks post tumor induction (shown at different magnifications) and of KPE mice (n = 5) at 12 weeks post tumor induction (shown at different magnifications).
Databáze: OpenAIRE