Quartz Whispering-Gallery-Mode Resonator with Microfluidic Chip as Sensor for Permittivity Measurement of Liquids
| Autor: | Svetlana Vitusevich, Alexandr A. Lavrinovich, Alexander A. Barannik, A. I. Gubin, Nickolay T. Cherpak, I. A. Protsenko |
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| Rok vydání: | 2022 |
| Předmět: |
Permittivity
Detection limit Physics - Instrumentation and Detectors Materials science business.industry 010401 analytical chemistry FOS: Physical sciences Physics - Applied Physics Dielectric resonator Dielectric Applied Physics (physics.app-ph) Instrumentation and Detectors (physics.ins-det) 01 natural sciences Temperature measurement 0104 chemical sciences Resonator Biological Physics (physics.bio-ph) Optoelectronics Physics - Biological Physics Electrical and Electronic Engineering Whispering-gallery wave business Instrumentation Microwave |
| DOI: | 10.48550/arxiv.2205.02463 |
| Popis: | Studies of biological solutions require high measurement accuracy, the ability to detect low changes in substance concentration, and small amounts of the liquid under test. A microwave complex permittivity measurement technique based on a high-quality-factor whispering-gallery-mode resonator with a microfluidic chip allows small amounts of dielectric liquids to be investigated with high accuracy. An existing technique based on a sapphire resonator does not provide for a low-concentration detection limit for substances with low molecular weight. Here, we present an advanced technique based on a quartz dielectric resonator. The detection limit obtained for glucose in water solution was found to be about one order of magnitude lower for the quartz resonator cell than for the sapphire-resonator-based measurement cell. The limit is about or lower than the concentration of glucose in human blood. This fact means that the technique can be used as the sensor for investigations of biological solutions in the microwave range. A study of glucose, lactalbumin, and bovine serum albumin was successfully performed in the $Ka$ -band using the developed sensor. |
| Databáze: | OpenAIRE |
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