Psychological distress of patients undergoing intensified conditioning with radioimmunotherapy prior to allogeneic stem cell transplantation
| Autor: | Donald Bunjes, Harald Bailer, N Grulke, H Kächele |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Coping (psychology) medicine.medical_specialty Time Factors Transplantation Conditioning medicine.medical_treatment Anxiety Internal medicine Surveys and Questionnaires Medicine Humans Transplantation Homologous Prospective cohort study Transplantation Leukemia business.industry Hematology Middle Aged Radioimmunotherapy Distress Conditioning Female medicine.symptom Stem cell business Stress Psychological Stem Cell Transplantation |
| Zdroj: | Bone marrow transplantation. 35(11) |
| ISSN: | 0268-3369 |
| Popis: | This is a pilot study comparing the emotional distress of patients receiving an intensified conditioning regimen (radioimmunotherapy=RIT) with patients receiving conventional conditioning for allogeneic stem cell transplantation. In total, 53 patients (18 received RIT) were given two questionnaires designed to measure emotional distress (HADS, POMS) before starting conditioning (t1) and at discharge (t2). During the in-patient period, patients answered questions daily relating to physical distress, psychological distress, and how they were ‘coping with the situation’. At t2, the transplant team assessed the manner in which the patients were coping. The data displayed no relevant differences with regard to emotional distress between the two groups, both at t1 and t2. For both groups, anxiety and vigor decreased and fatigue increased between t1 and t2. On average, perceived distress was higher for those patients being treated with RIT during the in-patient time, but the differences between both groups were significant only regarding physical distress during the recovery period. No difference was found for the transplant team's assessment. We hypothesize that an intensified conditioning regimen with RIT per se has only a small distressing effect on the patients’ psyche during their stay at the hospital. Differences between both groups probably result from independent factors such as, for example, the patients’ pre-existing health conditions. |
| Databáze: | OpenAIRE |
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