Afferent Connections of Cytoarchitectural Area 6M and Surrounding Cortex in the Marmoset: Putative Homologues of the Supplementary and Pre-supplementary Motor Areas
| Autor: | Kathleen J. Burman, Piotr Majka, Sylwia Bednarek, Natalia Jermakow, Sophia Bakola, Marcello G. P. Rosa, Katrina H. Worthy, Jonathan M. Chan |
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| Rok vydání: | 2021 |
| Předmět: |
Cognitive Neuroscience
Posterior parietal cortex Somatosensory system Gyrus Cinguli 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine biology.animal Cortex (anatomy) Parietal Lobe Neural Pathways medicine Animals 030304 developmental biology 0303 health sciences Motor area Supplementary motor area biology Motor Cortex Marmoset Motor control Callithrix SMA Retrograde tracing medicine.anatomical_structure Posterior cingulate Primary motor cortex Neuroscience 030217 neurology & neurosurgery Motor cortex |
| Zdroj: | Cerebral cortex (New York, N.Y. : 1991). 32(1) |
| ISSN: | 1460-2199 |
| Popis: | Cortical projections to the caudomedial frontal cortex were studied using retrograde tracers in marmosets. We tested the hypothesis that cytoarchitectural area 6M includes homologues of the supplementary and pre-supplementary motor areas (SMA and pre-SMA) of other primates. We found that, irrespective of the injection sites’ location within 6M, over half of the labeled neurons were located in motor and premotor areas. Other connections originated in prefrontal area 8b, ventral anterior and posterior cingulate areas, somatosensory areas (3a and 1–2), and areas on the rostral aspect of the dorsal posterior parietal cortex. Although the origin of afferents was similar, injections in rostral 6M received higher percentages of prefrontal afferents, and fewer somatosensory afferents, compared to caudal injections, compatible with differentiation into SMA and pre-SMA. Injections rostral to 6M (area 8b) revealed a very different set of connections, with increased emphasis on prefrontal and posterior cingulate afferents, and fewer parietal afferents. The connections of 6M were also quantitatively different from those of the primary motor cortex, dorsal premotor areas, and cingulate motor area 24d. These results show that the cortical motor control circuit is conserved in simian primates, indicating that marmosets can be valuable models for studying movement planning and control. |
| Databáze: | OpenAIRE |
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