Incidental focal FDG uptake in heart is a lighthouse for considering cardiac screening
| Autor: | Momoko Okasaki, Kimiteru Ito, Masao Moroi, Ryogo Minamimoto, Hisao Hara, Osamu Okazaki, Kazuo Kubota, Yoko Miyata, Miyako Morooka |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Heart Diseases Standardized uptake value Disease Muscle hypertrophy Coronary artery disease Fluorodeoxyglucose F18 medicine Humans Radiology Nuclear Medicine and imaging In patient Aged Aged 80 and over Incidental Findings PET-CT medicine.diagnostic_test business.industry Myocardium Fdg uptake Biological Transport General Medicine Middle Aged medicine.disease Positron emission tomography Positron-Emission Tomography Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Annals of Nuclear Medicine. 27:572-580 |
| ISSN: | 1864-6433 0914-7187 |
| Popis: | Cardiac FDG uptake is known to show a variety of patterns under clinical fasting conditions. We hypothesized that focal FDG uptake in the heart (FUH) represents a sign of cardiac disease risk, especially in coronary artery disease (CAD).The aim of this study was to clarify the relationship between FUH and cardiac disease. Cases showing FUH were selected based on comments in diagnostic reports or identification on retrospective review. Quantitative analysis was performed using maximum standardized uptake value (SUVmax), with regions of interest drawn over focal uptake areas in the heart as confirmed by PET/CT and in lateral side of the same slice showing focal FDG uptake. For the 20 patients (11 men, 9 women) with confirmed FUH, coronary artery stenosis or history of treatment for coronary disease was present in 11 patients (55.0 %), and 2 patients showed apical hypertrophy. Mean SUVmax of FUH did not differ significantly between patients with confirmed cardiac disease and those with no evidence of cardiac disease (P = 0.78). FUH suggests a high likelihood of CAD in patients without myocardial symptoms. Cardiac screening or a check of the history of cardiac disease is thus worth considering when FUH is seen incidentally on FDG-PET/CT. |
| Databáze: | OpenAIRE |
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