Feeding melancholic microbes: MyNewGut recommendations on diet and mood
| Autor: | Yolanda Sanz, Paul J. Kennedy, Caitlin S. M. Cowan, Jan Willem van der Kamp, Caitriona M. Long-Smith, María Carmen Cenit, John F. Cryan, Timothy G. Dinan, Catherine Stanton |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Mediterranean diet 030209 endocrinology & metabolism Gut microbiota Gut flora Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Environmental health medicine Humans Depression (differential diagnoses) chemistry.chemical_classification Brain Chemistry 030109 nutrition & dietetics Nutrition and Dietetics biology business.industry Depression MyNewGut Stress-related disorders medicine.disease biology.organism_classification Diet Gastrointestinal Microbiome Affect Mood chemistry Red meat Dysbiosis business Polyunsaturated fatty acid |
| Zdroj: | Clinical nutrition (Edinburgh, Scotland). 38(5) |
| ISSN: | 1532-1983 |
| Popis: | Summary: Depression is a highly prevalent disorder which exerts a major economic impact in all European countries. The brain-gut-microbiota axis has been described as a new paradigm for advancing understanding and treatment of the disorder. There is now over-whelming evidence to support the fact that gut microbes have a major impact on central neurochemistry and behaviour, especially stress related disorders such as depression. Recent studies indicate that patients with depression have a gut dysbiosis. The reason for this dysbiosis is uncertain. Over recent decades, dietary patterns in Europe and elsewhere have undergone major compositional changes, with increased intakes of red meat, high fat foods, and refined sugars. Individuals who consume a Mediterranean diet have lower rates of depression and a recent study suggests that a Mediterranean diet may have antidepressant properties. Assuming this to be the case, which components of the Mediterranean diet mediate the effects? Highly levels of polyphenols or polyunsaturated fatty acids are obvious candidates. We in the MyNewGut consortium recommend that patients with depression or vulnerability to depression should be encouraged to enhance a plant-based diet with a high content of grains/fibres and fish. |
| Databáze: | OpenAIRE |
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