Effects of AHCC® on Immune and Stress Responses in Healthy Individuals
| Autor: | J. Takanari, Shogo Miyazaki, Kazuo Uebaba, Tatsuya Hisajima, Hideaki Waki, Atsuya Sato |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Stress management
business.industry Period (gene) Physiology lcsh:RX1-681 lcsh:Other systems of medicine Placebo lcsh:RZ201-999 030226 pharmacology & pharmacy Sleep in non-human animals 03 medical and health sciences Parasympathetic nervous system 0302 clinical medicine Immune system medicine.anatomical_structure Complementary and alternative medicine Mechanism of action lcsh:Homeopathy medicine medicine.symptom business 030217 neurology & neurosurgery Depression (differential diagnoses) |
| Zdroj: | Journal of Evidence-Based Integrative Medicine, Vol 23 (2018) |
| Popis: | AHCC® is a functional food from the basidiomycete Lentinula edodes. We evaluated the effects of AHCC® on subjects under different kinds of stress and at rest. Physical stress was imposed using an active standing test, known as Schellong’s test. Sympathetic nervous activity in the standing position was significantly greater in AHCC®-treated subjects than in a placebo group. In contrast, AHCC® significantly increased parasympathetic nervous activity at rest. Under mental stress, AHCC® increased sympathetic nervous activity, with no difference in the parasympathetic nervous system. In subjects with chronic mental stress, self-reported “initiation and maintenance of sleep” was significantly greater in the AHCC®-intake period than in the placebo intake period, and natural killer cell activity also increased after AHCC® intake, suggesting a possible mechanism of action of AHCC®. Our findings indicate that AHCC® is potentially effective in stress management and may be useful in the treatment of depression. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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