Toward long-lasting artificial cells that better mimic natural living cells
| Autor: | Noël Yeh Martín, Luca Valer, Sheref S. Mansy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Long lasting artificial cell Population level Emerging technologies 02 engineering and technology Biology Chemical communication General Biochemistry Genetics and Molecular Biology Natural (archaeology) 03 medical and health sciences Synthetic biology Biochemical Techniques & Resources Artificial systems Chemical Biology Review Articles Artificial cell synthetic cells 021001 nanoscience & nanotechnology 030104 developmental biology artificial cell biotechnology synthetic biology synthetic cells Biochemical engineering synthetic biology 0210 nano-technology General Agricultural and Biological Sciences biotechnology |
| Zdroj: | Emerging Topics in Life Sciences |
| ISSN: | 2397-8554 |
| Popis: | Chemical communication is ubiquitous in biology, and so efforts in building convincing cellular mimics must consider how cells behave on a population level. Simple model systems have been built in the laboratory that show communication between different artificial cells and artificial cells with natural, living cells. Examples include artificial cells that depend on purely abiological components and artificial cells built from biological components and are driven by biological mechanisms. However, an artificial cell solely built to communicate chemically without carrying the machinery needed for self-preservation cannot remain active for long periods of time. What is needed is to begin integrating the pathways required for chemical communication with metabolic-like chemistry so that robust artificial systems can be built that better inform biology and aid in the generation of new technologies. |
| Databáze: | OpenAIRE |
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