Association between serum uric acid and cardiovascular disease risk factors in adolescents in America: 2001-2018

Autor: Ming Ye, Bing Jia, Ran Wang, Yaping Shan, Qiqi Shi, Huifeng Zhang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Epidemiology
Blood Pressure
Disease
Cardiovascular Medicine
Adolescents
Biochemistry
Vascular Medicine
Coronary artery disease
Families
chemistry.chemical_compound
Medical Conditions
Endocrinology
Medicine and Health Sciences
Insulin
Child
Children
Sex Characteristics
Multidisciplinary
Lipids
Chemistry
Cholesterol
Cardiovascular Diseases
Hypertension
Physical Sciences
Medicine
Female
Research Article
medicine.medical_specialty
Adolescent
National Health and Nutrition Examination Survey
Science
Cardiology
Preeclampsia
Internal medicine
Diabetes mellitus
medicine
Humans
Genetic Predisposition to Disease
Genetic Association Studies
Diabetic Endocrinology
business.industry
Cholesterol
HDL
Chemical Compounds
Biology and Life Sciences
Cardiovascular Disease Risk
medicine.disease
Hormones
Uric Acid
Glucose
Blood pressure
chemistry
Heart Disease Risk Factors
Age Groups
Medical Risk Factors
People and Places
Uric acid
Population Groupings
business
Acids
Kidney disease
Zdroj: PLoS ONE, Vol 16, Iss 8, p e0254590 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: SUA is associated with cardiovascular disease and cardiovascular disease risk factors in adults, including chronic kidney disease, coronary artery disease, stroke, diabetes mellitus, preeclampsia, and hypertension. A cross-sectional study was carried out among 11219 adolescents 12 to 18 years of age examined in the 2001–2018 National health and Nutrition Examination Survey. We examined the association between SUA and CVD risk factors. The overall mean SUA level was 5.00±1.24mg/dl. Restricted cubic spline analysis results revealed SUA was inversely associated with HDL-C and SPISE and positively associated with TC, TG, LDL-C, nonHDL-C, insulin, SBP and DBP after full adjustment. Multiple logistic analyses showed SUA level was independently associated with high TC, high TG, high nonHDL-C and low HDL-C (all p
Databáze: OpenAIRE
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