Multiple Origins of kdr-type Resistance in the House Fly, Musca domestica
| Autor: | Cheryl A. Leichter, Frank D. Rinkevich, Seán G. Brady, Vatan Taşkin, Shannon M. Hedtke, Cathy Su, Sarah A. Harris, Xinghui Qiu, Jeffrey G. Scott |
|---|---|
| Přispěvatelé: | MÜ |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Evolutionary Genetics
Integrated pest management Insecticides lcsh:Medicine Evolutionary Selection Voltage-Gated Sodium Channels Biochemistry Ion Channels Insecticide Resistance chemistry.chemical_compound Houseflies lcsh:Science Phylogeny Genetics Multidisciplinary Pyrethroid Phylogenetic tree Agriculture cardiovascular system Female Agrochemicals Musca Research Article circulatory and respiratory physiology Evolutionary Processes Biology Phylogenetics parasitic diseases Animals Pesticides neoplasms Alleles Evolutionary Biology business.industry Human evolutionary genetics lcsh:R fungi Haplotype Pest control [No Keywords] Proteins Haplotypes chemistry Cellular Neuroscience Mutation lcsh:Q Pest Control business Population Genetics Neuroscience |
| Zdroj: | PLoS ONE PLoS ONE, Vol 7, Iss 12, p e52761 (2012) |
| ISSN: | 0003-1305 |
| Popis: | WOS: 000313051500058 PubMed ID: 23285178 Insecticide resistance is a model phenotype that can be used to investigate evolutionary processes underlying the spread of alleles across a global landscape, while offering valuable insights into solving the problems that resistant pests present to human health and agriculture. Pyrethroids are one of the most widely used classes of insecticides world-wide and they exert their toxic effects through interactions with the voltage-sensitive sodium channel (Vssc). Specific mutations in Vssc (kdr, kdr-his and super-kdr) are known to cause resistance to pyrethroid insecticides in house flies. In order to determine the number of evolutionary origins of kdr, kdr-his and super-kdr, we sequenced a region of Vssc from house flies collected in the USA, Turkey and China. Our phylogenetic analysis of Vssc unequivocally supports the hypothesis of multiple independent origins of kdr, super-kdr and kdr-his on an unprecedented geographic scale. The implications of these evolutionary processes on pest management are discussed. Hatch projectUnited States Department of Agriculture (USDA) [139 7416] This work was supported by Hatch project 139 7416. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
| Databáze: | OpenAIRE |
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