Stabilizing effects in oxazolidin-2-ones-containing pseudopeptides
| Autor: | Chiara Soffrè, Gianluigi Luppi, Claudia Tomasini |
|---|---|
| Přispěvatelé: | G. Luppi, C. Soffrè, C. Tomasini |
| Rok vydání: | 2004 |
| Předmět: |
Circular dichroism
Hydrogen bond Stereochemistry Organic Chemistry CIRCULAR DICROISM Trans conformation GLYCINE Nuclear magnetic resonance spectroscopy Catalysis NMR SPECTROSCOPY Inorganic Chemistry OXAZOLIDIN-2-ONES chemistry.chemical_compound chemistry PSEUDOPEPTIDES Proton NMR Moiety Molecule Physical and Theoretical Chemistry Imide |
| Zdroj: | Tetrahedron: Asymmetry. 15:1645-1650 |
| ISSN: | 0957-4166 |
| Popis: | Novel homo-oligomers of the Gly-L-Oxd moiety have been prepared and their preferential conformations have been analyzed by IR, 1H NMR and CD spectroscopy, with the aim of checking whether these molecules are able to fold in ordered structures. We have noticed that in these homo-oligomers two stabilizing effects are active: besides the trans conformation of the imide group, the formation of C=O…H-N hydrogen bonds takes place and is very sensitive to the pseudopeptide size. |
| Databáze: | OpenAIRE |
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