An alternative efficient approach for the synthesis of Fingolimod hydrochloride

Autor:	Krishna Jonnada, Noorjahan Mohammed, Girija Mangatayaru Kotu, Krishna Vinigari
Rok vydání:	2019
Předmět:	Commercial scale 010405 organic chemistry Chemistry business.industry Fingolimod Hydrochloride Organic Chemistry 010402 general chemistry Process engineering business Alternative process Hardware_REGISTER-TRANSFER-LEVELIMPLEMENTATION 01 natural sciences 0104 chemical sciences
DOI:	10.6084/m9.figshare.7583126.v1
Popis:	An efficient process for the synthesis of API Fingolimod Hydrochloride is presented. This proposed synthesis involves simple commercially available octanophenone as a starting material. The route is effective involving seven steps to achieve the target, thus reducing the cycle time, and is cost efficient by 50%. It is an immune modulating drug for the treatment of heart failure and arrhythmias.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe8b602e22d635368bb22e0f4cac603 Zobrazit plný text záznamu