In vitro and clinical evaluation of optical tooth whitening toothpastes
| Autor: | Carole Jane Philpotts, Jianing N. Sun, Xiaojie Wang, Danying Tao, Qiong Zhang, Andrew Joiner, Mojgan A. Naeeni |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Toothbrushing business.product_category Adolescent Tooth colour Metalloporphyrins Color Dentistry Isoindoles Young Adult 03 medical and health sciences 0302 clinical medicine Double-Blind Method Tooth Bleaching Humans In vitro study Dental Pellicle 030212 general & internal medicine Coloring Agents General Dentistry Aged Tooth whitening Cross-Over Studies Toothpaste business.industry Chemistry Colorimeter 030206 dentistry Middle Aged Silicon Dioxide Drug Combinations Digital image analysis Blue covarine Tooth Discoloration Colorimetry Female business Tooth Clinical evaluation Color Perception Toothpastes |
| Zdroj: | Journal of Dentistry. 67:S25-S28 |
| ISSN: | 0300-5712 |
| DOI: | 10.1016/j.jdent.2017.08.014 |
| Popis: | To measure tooth whitening effects delivered immediately after brushing with silica-based toothpastes containing either blue covarine or a combination of blue covarine and FDC Blue No. 1 in vitro and in vivo.Salivary pellicle coated human extracted teeth were brushed with either a slurry of a toothpaste containing blue covarine (BC) or a formulation containing a matched level of blue covarine and FDC Blue No.1 (BC+D). The colour of the specimens were measured in vitro using a colorimeter, before and after brushing and changes in CIELAB and tooth Whiteness Index (WIO) values calculated. In a double-blind cross-over clinical study, subjects brushed with BC toothpaste, a toothpaste containing increased levels of blue covarine (BC+) or BC+D toothpaste and tooth colour changes were measured with a digital image analysis system.The in vitro study demonstrated that BC+D gave a significantly (p=0.002) greater change in WIO value than BC. Clinical results showed that BC, BC+ and BC+D gave a significant increase in WIO (p0.0001) from baseline. The WIO change was significantly greater when brushing with BC+D toothpaste than with either toothpaste BC (p0.0001) or BC+ (p0.05).Toothpastes containing blue covarine or a combination of blue covarine and FDC Blue No. 1 gave a statistically significant improvement in tooth whiteness immediately after brushing in both in vitro and clinical studies. In addition, the toothpaste containing both blue covarine and FDC Blue No. 1 gave statistically significant greater tooth whitening from baseline than the blue covarine containing toothpastes.The silica-based toothpastes containing blue covarine or a combination of blue covarine and FDC Blue No. 1 evaluated in the current study gave significant tooth whitening benefits immediately after one brush. |
| Databáze: | OpenAIRE |
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