Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes

Autor:	Dongbo Ding, Qing Li, Maggie Zi-Ying Chow, Kui Ming Chan, Junhong Han, Michael S.Y. Huen, Yuchen Zhang, Toyotaka Ishibashi, Du Yang, Tze Zhen Evangeline Kang, Yi Ching Esther Wan, Lina Zhu, Xin Wang, Jiaxian Liu, Zongli Zheng, Ajay Goel, Tsz Chui Sophia Leung, Chengmin Qian, Jitian Zhang, Xulun Sun
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Cancer Research Letter lcsh:Medicine medicine.disease_cause Histones 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Neoplasms Genetics medicine Humans Clustered Regularly Interspaced Short Palindromic Repeats Histone octamer Epigenetics Cancer genetics lcsh:QH301-705.5 030304 developmental biology Cell Proliferation 0303 health sciences Mutation biology lcsh:R Cancer Methylation DNA Oncogenes medicine.disease Phenotype Nucleosomes DNA-Binding Proteins Histone chemistry lcsh:Biology (General) 030220 oncology & carcinogenesis biology.protein Nucleic Acid Conformation
Zdroj:	Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-4 (2020) Signal Transduction and Targeted Therapy
ISSN:	2059-3635
DOI:	10.1038/s41392-020-0131-0
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe2f31ceb3225aa6b8641b95602b048 http://link.springer.com/article/10.1038/s41392-020-0131-0 Zobrazit plný text záznamu