Indole derivatives. 120. Synthesis of higher ω-(3-indolyl)alkanoic acids by alkylation of indole lactones
Autor: | B. Ya. Eryshev, N. N. Suvorov |
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Rok vydání: | 1980 |
Předmět: | |
Zdroj: | Chemistry of Heterocyclic Compounds. 16:158-160 |
ISSN: | 1573-8353 0009-3122 |
DOI: | 10.1007/bf02401692 |
Popis: | The alkylation of indole with the tridecanolide, pentadecanolide, and oxo lactones of ω-hydroxyethoxyundecanoic and ω-hydroxybutoxyundecanoic acids was investigated. Higher indolylalkanoic acids, viz., ω-(3-indolyl)undecanoic, ω-(3-indolyl)tride-canoic, and ω-(3-indolyl)pentadecanoic acids, were obtained. The scheme of the alkylation of indole with oxo lactones, and the difference in the rates of the reactions of the ester and lactone bonds, were established from the reaction products. |
Databáze: | OpenAIRE |
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