Indole derivatives. 120. Synthesis of higher ω-(3-indolyl)alkanoic acids by alkylation of indole lactones

Autor: B. Ya. Eryshev, N. N. Suvorov
Rok vydání: 1980
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 16:158-160
ISSN: 1573-8353
0009-3122
DOI: 10.1007/bf02401692
Popis: The alkylation of indole with the tridecanolide, pentadecanolide, and oxo lactones of ω-hydroxyethoxyundecanoic and ω-hydroxybutoxyundecanoic acids was investigated. Higher indolylalkanoic acids, viz., ω-(3-indolyl)undecanoic, ω-(3-indolyl)tride-canoic, and ω-(3-indolyl)pentadecanoic acids, were obtained. The scheme of the alkylation of indole with oxo lactones, and the difference in the rates of the reactions of the ester and lactone bonds, were established from the reaction products.
Databáze: OpenAIRE