Impact of different exercise intensities on pregnant rats and on their offspring
| Autor: | Elena Zambrano, Yuri Karen Sinzato, Gustavo Tadeu Volpato, A.O. Netto, Débora Cristina Damasceno, F. Q. Gallego, Nathália C. D. Macedo |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), Laboratório de Fisiologia dos Sistemas e Toxicologia Reprodutiva, Instituto Nacional de Ciências Médicas e Nutrição Salvador Zubirán |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
0301 basic medicine exercise intensities Offspring Science Physiology medicine.disease_cause 03 medical and health sciences Fetus 0302 clinical medicine medicine Animals Rats Wistar swimming Pregnancy 030219 obstetrics & reproductive medicine Multidisciplinary business.industry Reproduction Gestational age medicine.disease Rats Respiratory acidosis 030104 developmental biology Respiratory alkalosis fetuses Female pregnancy business Anaerobic exercise Oxidative stress |
| Zdroj: | Anais da Academia Brasileira de Ciências, Volume: 92, Issue: 4, Article number: e20191572, Published: 14 DEC 2020 Anais da Academia Brasileira de Ciências v.92 n.4 2020 Anais da Academia Brasileira de Ciências Academia Brasileira de Ciências (ABC) instacron:ABC Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Anais da Academia Brasileira de Ciências, Vol 92, Iss 4 (2020) |
| ISSN: | 0001-3765 |
| Popis: | Made available in DSpace on 2021-06-25T10:48:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01. Added 1 bitstream(s) on 2021-07-15T14:35:24Z : No. of bitstreams: 1 S0001-37652020000700932.pdf: 295985 bytes, checksum: 047baafb6147a16a795c3f86b32498e6 (MD5) Universidade Estadual Paulista Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) This study aimed at evaluating the levels of different maternal exercise intensities on maternal and fetal outcomes. Wistar rats were mated and the pregnant rats were distributed into four experimental groups (n = 13 animals/group): Control (Not exercise group-0% of the anaerobic threshold-AT), mild (20%), moderate (80%), and heavy-exercise intensity (140% of AT). These AT were matched to the load of 0, 1, 4 and 7% of the body weight of the animal related to swimming-induced physical intensity. In pregnancy, biomarkers related to maternal blood gases, oxidative stress, metabolism, and reproductive performance, and outcomes of their offspring were analyzed. The mild and moderate-swimming caused no change on implantation, live fetus numbers and oxidative stress status. However, the rats submitted to mild-exercise presented respiratory alkalosis and the heavy-exercise group showed respiratory acidosis. In addition, fetuses of the heavy-exercise dams were smaller for gestational age and lower serum adiponectin levels compared to those of other groups. In conclusion, the moderate-exercise intensity caused beneficial effects for maternal environment and the mild and moderate-exercise presented similar fetal repercussions. Nevertheless, the heavy-exercise intensity caused maternal metabolic alterations that damaged the fetal growth. Therefore, these findings confirm that physical intensity should be carefully conducted to avoid maternal complications and, consequently, compromised fetal repercussions. Universidade Estadual Paulista/ UNESP Laboratório de Pesquisa Experimental em Ginecologia e Obstetrícia, Distrito de Rubião Jr, s/n Universidade Federal do Mato Grosso/UFMT Instituto de Ciências Biológicas e da Saúde Laboratório de Fisiologia dos Sistemas e Toxicologia Reprodutiva, Av. Valdon Varjão, 6390 Instituto Nacional de Ciências Médicas e Nutrição Salvador Zubirán Departamento de Biologia Reprodutiva, Belisario Domínguez Secc, 16 Universidade Estadual Paulista/ UNESP Laboratório de Pesquisa Experimental em Ginecologia e Obstetrícia, Distrito de Rubião Jr, s/n CAPES: 001 FAPESP: 2012/25168-9 CNPq: 475073/2013-4 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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