Determination of anisotropic elastic parameters from morphological parameters of cancellous bone for osteoporotic lumbar spine
| Autor: | Stephan Schoenfelder, Christoph-Eckhard Heyde, Kerstin Funke, Michael Werner, Christoph Oefner, Elena Riemer |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Bone density Finite Element Analysis Homogenization theory Biomedical Engineering Homogenization (chemistry) Elastic anisotropy Lumbar Bone Density medicine Humans Anisotropy Lumbar Vertebrae Cancellous bone Biomechanics Fabric tensor Finite element method Computer Science Applications Osteoporotic spine medicine.anatomical_structure μCT Original Article Material properties Biomedical engineering |
| Zdroj: | Medical & Biological Engineering & Computing |
| ISSN: | 1741-0444 0140-0118 |
| DOI: | 10.1007/s11517-021-02465-0 |
| Popis: | In biomechanics, large finite element models with macroscopic representation of several bones or joints are necessary to analyze implant failure mechanisms. In order to handle large simulation models of human bone, it is crucial to homogenize the trabecular structure regarding the mechanical behavior without losing information about the realistic material properties. Accordingly, morphology and fabric measurements of 60 vertebral cancellous bone samples from three osteoporotic lumbar spines were performed on the basis of X-ray microtomography (μCT) images to determine anisotropic elastic parameters as a function of bone density in the area of pedicle screw anchorage. The fabric tensor was mapped in cubic bone volumes by a 3D mean-intercept-length method. Fabric measurements resulted in a high degree of anisotropy (DA = 0.554). For the Young’s and shear moduli as a function of bone volume fraction (BV/TV, bone volume/total volume), an individually fit function was determined and high correlations were found (97.3 ≤ R2 ≤ 99.1,p |
| Databáze: | OpenAIRE |
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