A brief history of bird flu
| Autor: | Florian Duchatel, Paul Digard, Samantha Lycett |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Reassortment
Bird migration Zoology Review Article avian influenza virus Biology medicine.disease_cause General Biochemistry Genetics and Molecular Biology Birds 03 medical and health sciences Influenza A Virus H1N1 Subtype Zoonoses Pandemic Influenza Human medicine Influenza A virus Animals Humans zoonotic Phylogeny 030304 developmental biology 0303 health sciences 030306 microbiology pandemic Outbreak Articles History 20th Century Influenza A virus subtype H5N1 3. Good health phylogenetics Viral phylodynamics Infectious disease (medical specialty) Influenza in Birds epidemiology General Agricultural and Biological Sciences |
| Zdroj: | Philosophical Transactions of the Royal Society B: Biological Sciences |
| ISSN: | 1471-2970 0962-8436 |
| Popis: | In 1918, a strain of influenza A virus caused a human pandemic resulting in the deaths of 50 million people. A century later, with the advent of sequencing technology and corresponding phylogenetic methods, we know much more about the origins, evolution and epidemiology of influenza epidemics. Here we review the history of avian influenza viruses through the lens of their genetic makeup: from their relationship to human pandemic viruses, starting with the 1918 H1N1 strain, through to the highly pathogenic epidemics in birds and zoonoses up to 2018. We describe the genesis of novel influenza A virus strains by reassortment and evolution in wild and domestic bird populations, as well as the role of wild bird migration in their long-range spread. The emergence of highly pathogenic avian influenza viruses, and the zoonotic incursions of avian H5 and H7 viruses into humans over the last couple of decades are also described. The threat of a new avian influenza virus causing a human pandemic is still present today, although control in domestic avian populations can minimize the risk to human health.This article is part of the theme issue ‘Modelling infectious disease outbreaks in humans, animals and plants: approaches and important themes’. This issue is linked with the subsequent theme issue ‘Modelling infectious disease outbreaks in humans, animals and plants: epidemic forecasting and control’. |
| Databáze: | OpenAIRE |
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