Healthcare-Associated SARS-CoV-2 Transmission-Experiences from a German University Hospital
| Autor: | Stefanie Kampmeier, Carlos L. Correa-Martínez, Alexander Mellmann, Marc T. Hennies, Vera Schwierzeck |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Attack rate Context (language use) healthcare-associated transmission Microbiology health care workers law.invention 03 medical and health sciences 0302 clinical medicine law Virology Pandemic Health care Epidemiology Ct-value Infection control Medicine 030212 general & internal medicine lcsh:QH301-705.5 attack rate business.industry SARS-CoV-2 Communication fungi Outbreak virus diseases COVID-19 030104 developmental biology Transmission (mechanics) lcsh:Biology (General) Emergency medicine business |
| Zdroj: | Microorganisms Microorganisms, Vol 8, Iss 1378, p 1378 (2020) |
| ISSN: | 2076-2607 |
| Popis: | During the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, healthcare systems worldwide have to prevent nosocomial SARS-CoV-2 transmission while maintaining duty of care. In our study, we characterize the transmission dynamic of SARS-CoV-2 in inpatients and healthcare workers (HCWs) at the University Hospital Münster (UHM) in northwest Germany. We identified 27 cases of healthcare-associated SARS-CoV-2 infections (4 inpatients and 23 HCWs) who had contact with patients and/or HCWs without the use of adequate PPE. The contacts of these index cases were followed up for SARS-CoV-2 infection after unprotected exposure and a quantitative measure of probability of becoming infected, the attack rate, was calculated. In addition, transmission was evaluated in the context of infection control measures established during the pandemic and we compared the epidemiological data of all index cases, including symptoms and Ct values of virology test results. The overall attack rate in the hospital setting was 1.3% (inpatients 0.9%, HCWs 1.6%). However, during an outbreak, the attack rate was 25.5% (inpatients 20.0%, HCWs 29.6%). For both scenarios, HCWs had a higher attack rate illustrating their role in healthcare-associated SARS-CoV-2 transmission. Taken together, our experiences demonstrate how infection control measures can minimize the transmission of SARS-CoV-2 in the healthcare setting. |
| Databáze: | OpenAIRE |
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