Quaternary Structure and Deoxyribonucleic Acid-Binding Properties of the Heme-Dependent, CO-Sensing Transcriptional Regulator PxRcoM

Autor: Matthew R. Dent, Madeleine G. Roberts, Hannah E. Bowman, Brian R. Weaver, Darrell R. McCaslin, Judith N. Burstyn
Rok vydání: 2022
Předmět:
Zdroj: Biochemistry. 61:678-688
ISSN: 1520-4995
0006-2960
DOI: 10.1021/acs.biochem.2c00086
Popis: RcoM, a heme-containing, CO-sensing transcription factor, is one of two known bacterial regulators of CO metabolism. Unlike its analogue CooA, the structure and DNA-binding properties of RcoM remain largely uncharacterized. Using a combination of size exclusion chromatography and sedimentation equilibrium, we demonstrate that RcoM-1 from
Databáze: OpenAIRE