Quaternary Structure and Deoxyribonucleic Acid-Binding Properties of the Heme-Dependent, CO-Sensing Transcriptional Regulator PxRcoM
Autor: | Matthew R. Dent, Madeleine G. Roberts, Hannah E. Bowman, Brian R. Weaver, Darrell R. McCaslin, Judith N. Burstyn |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Biochemistry. 61:678-688 |
ISSN: | 1520-4995 0006-2960 |
DOI: | 10.1021/acs.biochem.2c00086 |
Popis: | RcoM, a heme-containing, CO-sensing transcription factor, is one of two known bacterial regulators of CO metabolism. Unlike its analogue CooA, the structure and DNA-binding properties of RcoM remain largely uncharacterized. Using a combination of size exclusion chromatography and sedimentation equilibrium, we demonstrate that RcoM-1 from |
Databáze: | OpenAIRE |
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