Whole Blood Histamine Release Rate during Immunotherapy for Nasal Allergy
| Autor: | Megumi Takeda, Yoshihiro Ohashi, Yoshiaki Nakai, Takayuki Tamura, Hirokazu Sakamoto, Manabu Uekawa, Yusuke Esaki |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
Male Allergy Rhinitis Allergic Perennial Time Factors Adolescent medicine.medical_treatment Histamine Release chemistry.chemical_compound Humans Medicine In patient Child Desensitization (medicine) Whole blood business.industry General Medicine Nasal allergy Immunotherapy Middle Aged medicine.disease Nasal discharge Treatment Outcome Otorhinolaryngology chemistry Desensitization Immunologic Immunology Female business Histamine |
| Zdroj: | Acta Oto-Laryngologica. 111:202-208 |
| ISSN: | 1651-2251 0001-6489 |
| DOI: | 10.3109/00016489109134997 |
| Popis: | In treating nasal allergies, desensitization is widely used on a daily basis, and its efficacy has been highly valued. With the purpose of predicting therapeutic efficacy before carrying out immunotherapy, we compared whole blood histamine release rate and various subjective symptoms before and after immunotherapy. We also compared the degrees of efficacy. Immunotherapy brought about a tendency for a reduction in the whole blood histamine release rate. This tendency appeared most marked in those patients in whom an improvement of subjective symptoms was considerable. Among subjective symptoms, the reduction in whole blood histamine release rate was strongest against nasal discharge and sneezing. In patients with a low histamine release rate prior to the initiation of immunotherapy, the improvement in subjective symptoms tended to be low. |
| Databáze: | OpenAIRE |
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