Lack of association between occupational exposure to diesel exhaust and risk of pancreatic cancer: a systematic evaluation of available data
Autor: | Paolo Boffetta |
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Přispěvatelé: | Boffetta, P. |
Rok vydání: | 2013 |
Předmět: |
Male
medicine.medical_specialty Diesel exhaust pancreatic cancer Risk Assessment complex mixtures Occupational Exposure Pancreatic cancer Environmental health Epidemiology Confidence Intervals medicine Humans Vehicle Emissions Air Pollutants business.industry Public Health Environmental and Occupational Health Case-control study diesel exhaust medicine.disease Confidence interval Occupational Diseases Pancreatic Neoplasms Case-Control Studies Meta-analysis epidemiologic studie Female business Risk assessment Cohort study |
Zdroj: | International Archives of Occupational and Environmental Health. 87:455-462 |
ISSN: | 1432-1246 0340-0131 |
DOI: | 10.1007/s00420-013-0892-7 |
Popis: | Purpose: To review epidemiologic studies on risk of pancreatic cancer and occupational exposure to diesel exhaust. Methods: A literature search was conducted, and data were abstracted in a systematic fashion. Comparable results were combined using a random-effects meta-analysis. Results: Twenty-six studies were included in the review, including five studies based on routine statistics, 11 case-control studies [meta-relative risk (RR) of three estimates for diesel exhaust exposure 0.9; 95 % confidence interval (CI) 0.5, 1.6] and ten cohort studies (meta-RR of their results: 1.03; 95 % CI 0.93, 1.13). Few studies reported results according to duration of exposure or other quantitative measures; no consistent pattern emerged. Conclusions: The overall evidence from studies on occupational exposure to diesel exhaust and risk of pancreatic cancer leads to the conclusion of the absence of such association. © 2013 Springer-Verlag Berlin Heidelberg. |
Databáze: | OpenAIRE |
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