Prediction of Pain and Opioid Utilization in the Perioperative Period in Patients Undergoing Primary Knee Arthroplasty: Psychophysical and Psychosocial Factors
| Autor: | Claudia M. Campbell, Richard D. Urman, Robert R. Edwards, Christopher R. Abrecht, Robert N. Jamison, Jennifer A. Haythornthwaite, Michael T. Smith, Kristin L. Schreiber, David Janfaza, Albert Wu, Marise Cornelius |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Total Knee Arthroplasty medicine.medical_treatment Replacement ACUTE & PERIOPERATIVE PAIN SECTION Osteoarthritis Cohort Studies 0302 clinical medicine Anesthesiology 030202 anesthesiology Arthroplasty Replacement Knee Pain Measurement Analgesics Postoperative Pain Pain Postoperative Pain Research Pharmacology and Pharmaceutical Sciences General Medicine Middle Aged predictors of acute pain Acute Pain Analgesics Opioid Public Health and Health Services Female Patient Safety Chronic Pain Psychosocial Cohort study medicine.drug medicine.medical_specialty Clinical Sciences Pain Opioid Arthroplasty 03 medical and health sciences Clinical Research Internal medicine medicine Humans Knee Postoperative Perioperative Period Quantitative Sensory Testing Aged business.industry Prevention Arthritis Neurosciences Perioperative medicine.disease Chronic Post-Surgical Pain Anesthesiology and Pain Medicine Musculoskeletal Neuralgia Neurology (clinical) business Body mass index Somatization 030217 neurology & neurosurgery |
| Zdroj: | Pain medicine (Malden, Mass.), vol 20, iss 1 |
| Popis: | OBJECTIVE: To identify factors associated with pain severity and opioid consumption in the early perioperative period. DESIGN: Prospective observational cohort study. SETTING: Tertiary academic medical center. SUBJECTS: Patients with osteoarthritis older than age 45 years undergoing primary total knee replacement at Brigham and Women’s Hospital. A total of 126 patients enrolled. METHODS: Preoperatively, pain questionnaires and quantitative sensory testing were performed on patients to develop a psychosocial and psychophysical profile. Postoperatively, pain scores and opioid consumption were measured as primary end points. Univariate and multiple linear regression analyses were performed to determine the predictive value of these characteristics on perioperative pain scores and opioid consumption. RESULTS: Regression analysis revealed several predictors of acute postoperative pain scores including temporal summation of pain (TSP; P = 0.001), body mass index (BMI; P = 0.044), number of previous knee surgeries (P = 0.006), and female gender (P = 0.023). Similarly, predictors of opioid utilization included TSP (P = 0.011), BMI (P = 0.02), age (P = |
| Databáze: | OpenAIRE |
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